LQ15H280003), the Clinical Research Projects of Zhejiang Medical Association (No. MANILA, Philippines The Makati Medical Center's therapeutics and medication safety committee (TMSC) has said that the Chinese drug, Lianhua Qingwen (LQ), should not be taken without a doctor's prescription to ease new coronavirus disease (COVID-19) symptoms, warning that it may do more harm than good. doi:10.19803/j.1672-8629.2015.12.011, Rivera, D., Allkin, R., Obn, C., Alcaraz, F., Verpoorte, R., and Heinrich, M. (2014). Individuals w/ cold deficiencies in spleen & stomach or w/ qi. Analysis of Clinical Application and Adverse Reactions of Houttuynia Cordata Injection. LHQW has been recommended by the China International Exchange and Promotive Association for Medical and Health Care and the Chinese Research Hospital Association as comprehensive treatment for moderate or chronic COVID-19 pneumonia in conjunction with routine therapy (Jin et al., 2020). 6 (26), 8485. Wang et al. Mo H.Y., Yang Z.F., Zheng J.P., Mo Z.Y., Li Y.M., Xiao Z.L. Li L.C., Kan L.D. An article on telemedicine and medical news platform Dr. Lilac pointed out that there was no scientific evidence available to indicate that LHQW was effective as prophylaxis to prevent infection, nor did there exist any official government recommendation for such usage; instead, taking the drug unnecessarily carried a risk of side effects. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. 367 (6485), 14121413. (2010). Besides, on April 14, 2020, the National Medical Products Administration of China approved modifying the specification of LHQW (Yiling Pharmaceutical Inc.) by adding a new indication for COVID-19 treatment in mild and normal cases. The https:// ensures that you are connecting to the Dang Y., Xu J., Yang Y., Li C., Zhang Q., Zhou W., Zhang L., Ji G. Ling-gui-zhu-gan decoction alleviates hepatic steatosis through SOCS2 modification by N6-methyladenosine. Traditional Chin. BMJ. ChemRxiv. The Plant List (2021). Statistical analysis was performed with Stata 14 software (Stata Corporation, College Station, TX, USA). Wang F.C., Shen B.X., He C.Y., Zhao W.C., Nie S.L. Systematic Review Registration: https://clinicaltrials.gov/, CRD-42020224180. Available at: http://www.plantsoftheworldonline.org (Accessed December 18, 2021). Systematic review of traditional Chinese medicine Lianhua Qingwen in Peng L.L., Li L., Shen L., Li X.L. Traditional Chinese medicine for pulmonary fibrosis therapy: progress and future prospects. doi:10.1111/j.0006-341x.2000.00455.x, Fan, Z., Guo, G., Che, X., Yang, Y., Liu, Y., Li, L., et al. The mechanisms were mainly involved the antiviral activity, and regulation of inflammation response as well as immune function. Subgroup analysis additionally revealed a reduced incidence of some adverse reactions in the LHQW group compared to the conventional drug group (Rash of skin and its appendage damage, dizziness or headache owing to nervous system damage, nausea or vomiting from gastrointestinal system damage and resurgence of disease from other adverse reactions). The search keywords for screening the literature information were virus, COVID-19, or SARS-CoV-2, and Lianhua Qingwen.
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