Saad Z. Usmani, MD. Beth Faiman Discusses Recent Changes in Multiple Myeloma Treatment Landscape. Nurses should encourage patients to incorporate thin liquids into their diet. But neither are expected to give the cash-strapped company significant revenue, making a third program for sickle cell disease crucial to its future. Injection-site reactions were observed in 7.9% of patients. Diagnosis and Management of Adult Malignancy-Associated Hemophagocytic Lymphohistiocytosis. "Hydrate, hydrate, hydrate," she said. Talquetamab generates high response rate in patients with hard-to-treat Ive been on pretty much every approved drug regimen and theyve all worked really well for me. The 73% response rate in this study is higher than that for most currently available therapies. She [noted] that that would increase the incidence of fungal issues. This year, among the several bi-specifics on the ASH agenda, Talquetamab still peaks my interest. Before Talquetamab Study in RRMM | Int'l Myeloma Foundation In the phase 1 trial, 232 patients with relapsed or refractory myeloma were given talquetamab. For example, skin and ear problems, which can sometimes affect patients a little bit differently, but can also be a quality-of-life issue. Additionally, Shain said that patients on other BiTE therapies may experience an increased risk of infection, as well as rashes, nail issues, loss of taste and other side effects all of which should be brought up to the health care team to ensure that patients can remain on therapy. We are getting into the realm of treatment in myeloma where the newer drugs are sometimes coming up with unique side effects. 2023 Apr 28. doi: 10.1007/s00277-023-05218-1. Emerging Strategies to Manage Relapsed and/or Refractory Multiple Myeloma. The same side effects that I mentioned are cytokine release syndrome. Known in full as G protein-coupled receptor, family C, group 5, member D, the protein found on cancerous plasma cells drew attention over the weekend as Johnson & Johnson unveiled new data for an experimental multiple myeloma treatment.
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